Υποτροπή ή παρένθεση; (Εξελίξεις)

Εξελίξεις - Αλληλογραφία με τον θεράποντα ιατρό στις ΗΠΑ

October 10, 2007

Dear Doctor K.,

I hope you and your family are in great health.

I am writing to inform you about my daughter’s health condition.
To remind you, we have been in Mayo Clinic last April and she was under your care.

Your final diagnoses were:
Symptomatic generalized epilepsy
Developmental delay
Microscopic hematuria, probably related to Topiramate

My daughter's current medications are:
1)Topamax 25 mg a.m. and 50 mg p.m.
2)Depakote Sprinkles 125 mg a.m. and 250 mg p.m.
3)Ketogenic Diet

On September 29 she had a tonic-clonic seizure due to high temperature (38 C). She was given rectal diazepam 10 ml twice, in order to stop the seizure.

On October 9 she had another episode, which lasted 6 min, but with no fever this time. Again she was given twice rectal diazepam 10 ml.

My concern is:
Can we assume that these seizures are a result of the reduction of Topamax?
Since the 1st of July 2007 we have reduced the dose of Topamax, as shown above.

I would very much appreciate if you could send me your opinion on the matter.

Thank you for your time!

Sincerely

A.
(mother)

---------------.

10/10/07

Dear Ms. A.,

It is possible that lowering the Topamax has made Maria-Fotini more prone to seizures. Given the fact that she had microscopic hematuria, we have had no choice. I would recommend that the dose of Depakote be increased to 250 mg in am, 250 mg in pm. This will hopefully prevent further seizures. Also, a good idea to check a serum valproic acid (Depakote) level in about one week.

Sincerely,
S.K